Focal therapy is a promising option for selected patients who have localized low or intermediate risk prostate cancer providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible numerous cohort. In field failure as either cancer with a higher gleason grade persistent cancer of a similar or lower grade after repeat focal therapy to the same area or the need for additional pca treatment other than focal therapy because of objective findings elsewhere in the gland eg high grade cancer. Technical aspects of focal therapy in localized prostate cancer follow up after focal therapy lukman hakim lorenzo tosco wahjoe djatisoesanto thomas van den broeck willemien van den bos maarten albersen et al pages 199 208 failure or recurrence management. Over the last few years the concept of focal therapy for the treatment of prostate cancer pca has gained popularity and has been increasingly implemented in the field of locali